MILD COGNITIVE IMPAIRMENT and QEEG

MILD COGNITIVE IMPAIRMENT and QEEG

Mild cognitive impairment is an intermediate stage between normal aging and dementia, it shows a decrease in
cognitive function including memory, but the ability to perform daily activities is preserved. It is known that 80% of
patients develop Alzheimer’s dementia disease within 6 years after diagnosis of mild cognitive impairment.

However, even with mild cognitive impairment, there is a difference in the morbidity between Alzheimer MCI, and
None-Alzheimer MCI. This can be distinguished by the Al model based on QEEG learning.

According to preceding QEEG research, EEG shows sensitive changes from when functional deterioration occurs
before severe structural changes happen in the brain. ‘Slowing brainwaves’ is the main feature, and it is observed
as below.

with Healthy aging people’s EEG, normal brain waves such as alpha wave is observed.
with Mild cognitive impairment patient’s EEG, slow wave such as theta wave is observed.
with Alzheimer’s dementia patient’s EEG, very slow wave such as delta wave and theta wave are observed.

CASE REVIEW

Participant information
– Age: 80 / Male / Diagnosed with mild cognitive impairment (Alzheimer MCI)
– Age: 75/Female / Diagnosed with mild cognitive impairment (None-Alzheimer MCI)

None-Alzheimer MCI

| aMCI Screening

Compared to healthy people, an increase of slow wave
which is theta wave and alpha 1 wave was observed in both
temporal lobes.

Compared to healthy people, beta waves are generally
activated because beta waves generated from the healthy
brain regions, compensate the EEG slowness in the early
stages of mild cognitive impairment.

| Band Power – Topomap

Alzheimer MCI

| aMCI Screening

Compared to healthy people, in both temporal lobes,
an increase of slow wave which is theta wave and alpha 1 wave,
and in the frontal lobe, an increase of delta wave was observed.
Compared to healthy people, beta waves generally decrease.

This means that as mild cognitive impairment progresses
EEG slows down, and the compensation effect of
beta waves generated from healthy brain regions decreases,